Ontology highlight
ABSTRACT:
SUBMITTER: Schwaner E
PROVIDER: S-EPMC5585174 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Schwaner Endre E Németh Zsuzsanna Z Jani Péter K PK Kajdácsi Erika E Debreczeni Márta L ML Doleschall Zoltán Z Dobó József J Gál Péter P Rigó János J András Kinga K Hegedűs Tamás T Cervenak László L
Scientific reports 20170905 1
Mannan-binding lectin-associated serine protease 1 (MASP-1), the most abundant enzyme of the complement lectin pathway, is able to stimulate human umbilical vein endothelial cells (HUVECs) to alter the expression of several cytokines and adhesion molecules. This study has assessed to what extent MASP-1 is able to modify the transcriptional pattern of inflammation-related (IR) genes in HUVECs. We utilized Agilent microarray to analyse the effects of recombinant MASP-1 (rMASP-1) in HUVECs, on a se ...[more]