Ontology highlight
ABSTRACT:
SUBMITTER: Rossi BM
PROVIDER: S-EPMC5586063 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Rossi Benedito Mauro BM Palmero Edenir Inêz EI López-Kostner Francisco F Sarroca Carlos C Vaccaro Carlos Alberto CA Spirandelli Florencia F Ashton-Prolla Patricia P Rodriguez Yenni Y de Campos Reis Galvão Henrique H Reis Rui Manuel RM Escremim de Paula André A Capochin Romagnolo Luis Gustavo LG Alvarez Karin K Della Valle Adriana A Neffa Florencia F Kalfayan Pablo German PG Spirandelli Enrique E Chialina Sergio S Gutiérrez Angulo Melva M Castro-Mujica Maria Del Carmen MDC Sanchez de Monte Julio J Quispe Richard R da Silva Sabrina Daniela SD Rossi Norma Teresa NT Barletta-Carrillo Claudia C Revollo Susana S Taborga Ximena X Morillas L Lena LL Tubeuf Hélène H Monteiro-Santos Erika Maria EM Piñero Tamara Alejandra TA Dominguez-Barrera Constantino C Wernhoff Patrik P Martins Alexandra A Hovig Eivind E Møller Pål P Dominguez-Valentin Mev M
BMC cancer 20170905 1
<h4>Background</h4>Genetic counselling and testing for Lynch syndrome (LS) have recently been introduced in several Latin America countries. We aimed to characterize the clinical, molecular and mismatch repair (MMR) variants spectrum of patients with suspected LS in Latin America.<h4>Methods</h4>Eleven LS hereditary cancer registries and 34 published LS databases were used to identify unrelated families that fulfilled the Amsterdam II (AMSII) criteria and/or the Bethesda guidelines or suggestive ...[more]