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Experimental modulation and computational model of nano-hydrophobicity.


ABSTRACT: We demonstrate that nano-hydrophobicity, which governs the biological aggressiveness of nanoparticles, is determined by the outermost regions of surface ligands. We have also successfully modulated nano-hydrophobicity using systematic surface ligand modifications and built the first computational model of nano-hydrophobicity.

SUBMITTER: Li S 

PROVIDER: S-EPMC5586105 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature

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Experimental modulation and computational model of nano-hydrophobicity.

Li Shuhuan S   Zhai Shumei S   Liu Yin Y   Zhou Hongyu H   Wu Jinmei J   Jiao Qing Q   Zhang Bin B   Zhu Hao H   Yan Bing B  

Biomaterials 20150228


We demonstrate that nano-hydrophobicity, which governs the biological aggressiveness of nanoparticles, is determined by the outermost regions of surface ligands. We have also successfully modulated nano-hydrophobicity using systematic surface ligand modifications and built the first computational model of nano-hydrophobicity. ...[more]

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