Ontology highlight
ABSTRACT:
SUBMITTER: Linn KA
PROVIDER: S-EPMC5586239 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Linn Kristin A KA Laber Eric B EB Stefanski Leonard A LA
Journal of the American Statistical Association 20170331 518
A dynamic treatment regime is a sequence of decision rules, each of which recommends treatment based on features of patient medical history such as past treatments and outcomes. Existing methods for estimating optimal dynamic treatment regimes from data optimize the mean of a response variable. However, the mean may not always be the most appropriate summary of performance. We derive estimators of decision rules for optimizing probabilities and quantiles computed with respect to the response dis ...[more]