Ontology highlight
ABSTRACT:
SUBMITTER: Ortiz C
PROVIDER: S-EPMC5587298 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Ortiz Cristina C Casanova Mercedes M Palacios Pilar P Vicente Miguel M
PloS one 20170906 9
Assembly of the proto-ring, formed by the essential FtsZ, FtsA and ZipA proteins, and its progression into a divisome, are essential events for Escherichia coli division. ZapC is a cytoplasmic protein that belongs to a group of non-essential components that assist FtsZ during proto-ring assembly. Any overproduction of these proteins leads to faulty FtsZ-rings, resulting in a cell division block. We show that ZapC overproduction can be counteracted by an excess of the ZipA-independent hypermorph ...[more]