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DNA based multi-copper ions assembly using combined pyrazole and salen ligandosides.

ABSTRACT: The DNA structure is an ideal building block for the construction of functional nano-objects. In this direction, metal coordinating base pairs (ligandosides) are an appealing tool for the future specific functionalization of such nano-objects. We present here a study, in which we combine the metal ion coordinating pyrazole ligandoside with the interstrand crosslinking salen ligandoside system. We show that both ligandosides, when combined, are able to create stable multi-copper ion complexing DNA double helix structures in a cooperative fashion.

SUBMITTER: Su M

PROVIDER: S-EPMC5588782 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature

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DNA based multi-copper ions assembly using combined pyrazole and salen ligandosides.

Su Meng M Tomás-Gamasa María M Carell Thomas T

Chemical science 20140811 1

The DNA structure is an ideal building block for the construction of functional nano-objects. In this direction, metal coordinating base pairs (ligandosides) are an appealing tool for the future specific functionalization of such nano-objects. We present here a study, in which we combine the metal ion coordinating pyrazole ligandoside with the interstrand crosslinking salen ligandoside system. We show that both ligandosides, when combined, are able to create stable multi-copper ion complexing DN ...[more]

PMID: 28936312

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