Ontology highlight
ABSTRACT:
SUBMITTER: Aw Yong KM
PROVIDER: S-EPMC5589910 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Scientific reports 20170907 1
The analysis of invading leader cells at the tumor invasion front is of significant interest as these cells may possess a coordinated functional and molecular phenotype which can be targeted for therapy. However, such analyses are currently limited by available technologies. Here, we report a fluidic device for long-term three-dimensional tumoroid culture which recapitulated the tumor invasion front, allowing for both quantification of invasive potential and molecular characterization of invasiv ...[more]