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Voluntary liquorice ingestion increases blood pressure via increased volume load, elevated peripheral arterial resistance, and decreased aortic compliance.


ABSTRACT: We investigated the haemodynamic effects of two-week liquorice exposure (glycyrrhizin dose 290-370?mg/day) in 22 healthy volunteers during orthostatic challenge. Haemodynamics were recorded during passive 10-minute head-up tilt using radial pulse wave analysis, whole-body impedance cardiography, and spectral analysis of heart rate variability. Thirty age-matched healthy subjects served as controls. Liquorice ingestion elevated radial systolic (p?

SUBMITTER: Hautaniemi EJ 

PROVIDER: S-EPMC5591274 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature

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Voluntary liquorice ingestion increases blood pressure via increased volume load, elevated peripheral arterial resistance, and decreased aortic compliance.

Hautaniemi Elina J EJ   Tahvanainen Anna M AM   Koskela Jenni K JK   Tikkakoski Antti J AJ   Kähönen Mika M   Uitto Marko M   Sipilä Kalle K   Niemelä Onni O   Mustonen Jukka J   Pörsti Ilkka H IH  

Scientific reports 20170908 1


We investigated the haemodynamic effects of two-week liquorice exposure (glycyrrhizin dose 290-370 mg/day) in 22 healthy volunteers during orthostatic challenge. Haemodynamics were recorded during passive 10-minute head-up tilt using radial pulse wave analysis, whole-body impedance cardiography, and spectral analysis of heart rate variability. Thirty age-matched healthy subjects served as controls. Liquorice ingestion elevated radial systolic (p < 0.001) and diastolic (p = 0.018) blood pressure  ...[more]

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