Diffusion weighted imaging in patients with rectal cancer: Comparison between Gaussian and non-Gaussian models.

ABSTRACT:

Purpose

The purpose of this study was to compare the performance of four diffusion models, including mono and bi-exponential both Gaussian and non-Gaussian models, in diffusion weighted imaging of rectal cancer.

Material and methods

Nineteen patients with rectal adenocarcinoma underwent MRI examination of the rectum before chemoradiation therapy including a 7 b-value diffusion sequence (0, 25, 50, 100, 500, 1000 and 2000 s/mm2) at a 1.5T scanner. Four different diffusion models including mono- and bi-exponential Gaussian (MG and BG) and non-Gaussian (MNG and BNG) were applied on whole tumor volumes of interest. Two different statistical criteria were recruited to assess their fitting performance, including the adjusted-R2 and Root Mean Square Error (RMSE). To decide which mo

SUBMITTER: Manikis GC 

PROVIDER: S-EPMC5593499 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature