Ontology highlight
ABSTRACT:
SUBMITTER: Wang F
PROVIDER: S-EPMC5593541 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Oncotarget 20170628 34
Renal cell carcinoma (RCC) is considered a cytokine-responsive tumor. However, with the lack of diagnostic screening biomarkers, early diagnosis of RCC is challenging. Our study was investigated the association of IL1 gene polymorphisms and RCC risk. We conducted a case-control study of 291 RCC cases and 463 controls to evaluation the IL1RN of single nucleotide polymorphisms (SNPs) on RCC risk. We selection of 16 SNPs in IL1RN, IL1A, IL1B genes were analyzed. Using the chi-squared (χ<sup>2</sup> ...[more]