Ontology highlight
ABSTRACT:
SUBMITTER: Cai J
PROVIDER: S-EPMC5593601 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Cai Jiarong J Ye Qingjian Q Luo Suling S Zhuang Ze Z He Kui K Zhuo Zhen-Jian ZJ Wan Xiaochun X Cheng Juan J
Oncotarget 20170525 34
The <i>CASP8</i> -652 6N insertion/deletion (I/D) polymorphism reduces expression of caspase 8. We conducted a meta-analysis to clarify the relationship between this polymorphism and cancer risk. Eligible articles were retrieved from PubMed, EMBASE, CNKI, and WANFANG databases through February 2017. A total of 33 articles with 49 studies, including 33,494 cases and 36,397 controls, were analyzed. We found that the <i>CASP8</i> -652 6N ins/del polymorphism was associated with decreased overall ca ...[more]