Ontology highlight
ABSTRACT:
SUBMITTER: Vo TTL
PROVIDER: S-EPMC5593637 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Vo Tam Thuy Lu TTL Park Ji-Hyeon JH Seo Ji Hae JH Lee Eun Ji EJ Choi Hoon H Bae Sung-Jin SJ Le Hoang H An Sunho S Lee Hye Shin HS Wee Hee-Jun HJ Kim Kyu-Won KW
Oncotarget 20170718 34
Aurora kinase A (AuA) is a prerequisite for centrosome maturation, separation, and mitotic spindle assembly, thus, it is essential for cell cycle regulation. Overexpression of AuA is implicated in poor prognosis of many types of cancer. However, the regulatory mechanisms underlying the functions of AuA are still not fully understood. Here, we report that AuA colocalizes with arrest defective protein 1 (ARD1) acetyltransferase during cell division and cell migration. Additionally, AuA is acetylat ...[more]