Ontology highlight
ABSTRACT:
SUBMITTER: Camilleri M
PROVIDER: S-EPMC5595063 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Neurogastroenterology and motility 20120601 6
Defects in intestinal barrier function are associated with diseases of the gastrointestinal (GI) tract. There is growing evidence that increases in intestinal permeability plays a pathogenic role in diseases, such as inflammatory bowel disease (IBD) and celiac disease, and functional bowel disorders, such as irritable bowel syndrome (IBS). This review takes a unique translational approach to discuss the physiological and pathophysiological mechanisms involved in the regulation of intestinal barr ...[more]