Intestinal barrier function in health and gastrointestinal disease.
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ABSTRACT:
SUBMITTER: Camilleri M
PROVIDER: S-EPMC5595063 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Publications
Intestinal barrier function in health and gastrointestinal disease.
Camilleri M M Madsen K K Spiller R R Greenwood-Van Meerveld B B Verne G N GN
Neurogastroenterology and motility 20120601 6
Defects in intestinal barrier function are associated with diseases of the gastrointestinal (GI) tract. There is growing evidence that increases in intestinal permeability plays a pathogenic role in diseases, such as inflammatory bowel disease (IBD) and celiac disease, and functional bowel disorders, such as irritable bowel syndrome (IBS). This review takes a unique translational approach to discuss the physiological and pathophysiological mechanisms involved in the regulation of intestinal barr ...[more]
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