A Review of Mitochondrial Optic Neuropathies: From Inherited to Acquired Forms.
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SUBMITTER: Pilz YL
PROVIDER: S-EPMC5595256 | biostudies-literature | 2017 Oct - Dec
REPOSITORIES: biostudies-literature
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A Review of Mitochondrial Optic Neuropathies: From Inherited to Acquired Forms.
Pilz Yasmine L YL Bass Sherry J SJ Sherman Jerome J
Journal of optometry 20161228 4
In recent years, the term mitochondrial optic neuropathy (MON) has increasingly been used within the literature to describe a group of optic neuropathies that exhibit mitochondrial dysfunction in retinal ganglion cells (RGCs). Interestingly, MONs include genetic aetiologies, such as Leber hereditary optic neuropathy (LHON) and dominant optic atrophy (DOA), as well as acquired aetiologies resulting from drugs, nutritional deficiencies, and mixed aetiologies. Regardless of an inherited or acquired ...[more]
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