Molecular conservation of marsupial and eutherian placentation and lactation.
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ABSTRACT:
SUBMITTER: Guernsey MW
PROVIDER: S-EPMC5595433 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Publications
Molecular conservation of marsupial and eutherian placentation and lactation.
Guernsey Michael W MW Chuong Edward B EB Cornelis Guillaume G Renfree Marilyn B MB Baker Julie C JC
eLife 20170912
Eutherians are often mistakenly termed 'placental mammals', but marsupials also have a placenta to mediate early embryonic development. Lactation is necessary for both infant and fetal development in eutherians and marsupials, although marsupials have a far more complex milk repertoire that facilitates morphogenesis of developmentally immature young. In this study, we demonstrate that the anatomically simple tammar placenta expresses a dynamic molecular program that is reminiscent of eutherian p ...[more]
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