Ontology highlight
ABSTRACT:
SUBMITTER: Gao X
PROVIDER: S-EPMC5598402 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Gao Xiugong X Yourick Jeffrey J JJ Topping Vanessa D VD Black Thomas T Olejnik Nicholas N Keltner Zachary Z Sprando Robert L RL
Toxicology reports 20141219
Male and female rats (26-day-old) were exposed to 0.0, 0.4, 4 or 40 mg/kg body weight silver acetate (AgAc) in drinking water for 10 weeks prior to and during mating. Sperm-positive females remained within their dose groups and were exposed to silver acetate during gestation and lactation. At postnatal day 26, the effect of silver ions on the developing F1 generation rat thymus was evaluated at the transcriptional level using whole-genome microarrays. Gene expression profiling analyses identifie ...[more]