Ontology highlight
ABSTRACT:
SUBMITTER: Majeed M
PROVIDER: S-EPMC5598428 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Majeed Muhammed M Nagabhushanam Kalyanam K Natarajan Sankaran S Bani Sarang S Pandey Anjali A Karri Suresh Kumar SK
Toxicology reports 20150402
The present work investigated repeated dose and reproductive toxicity of Calebin A in Wistar rats. A study for assessing the mutagenic potential of Calebin A through an AMES test is also described. Calebin A was orally administered to groups of 10 male and/or 10 female Wistar rats each, assigned to three dose levels (20, 50 and 100 mg/kg/body weight) once daily for 90 consecutive days. None of the animals in any of the treatment/control groups exhibited any abnormal clinical signs/behavioral cha ...[more]