Ontology highlight
ABSTRACT:
SUBMITTER: Buranatragool K
PROVIDER: S-EPMC5598537 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Toxicology reports 20150102
Zearalenone (ZEA) is a secondary fungal metabolite produced mainly by a <i>Fusarium graminearum</i>. To clarify the toxicokinetics, and residues of ZEA and its major metabolites α-zearalenol (α-ZOL) and β-zearalenol (β-ZOL) in chickens, ZEA was then administered intravenously (iv) or orally (po) to broiler chickens at a dosage of 1.2 mg/kg body weight. The concentrations of ZEA, α-ZOL and β-ZOL in the plasma and various tissues were quantified using LC-MS/MS. The plasma concentrations of ZEA wer ...[more]