Ontology highlight
ABSTRACT:
SUBMITTER: Ichise H
PROVIDER: S-EPMC5599245 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Ichise Hiroshi H Nagano Seiji S Maeda Takuya T Miyazaki Masaki M Miyazaki Yuki Y Kojima Hiroto H Yawata Nobuyo N Yawata Makoto M Tanaka Hidenori H Saji Hiroh H Masuda Kyoko K Kawamoto Hiroshi H
Stem cell reports 20170831 3
HLA haplotype-homozygous (HLA-homo) induced pluripotent stem cells (iPSCs) are being prepared to be used for allogeneic transplantation of regenerated tissue into recipients carrying an identical haplotype in one of the alleles (HLA-hetero). However, it remains unaddressed whether natural killer (NK) cells respond to these regenerated cells. HLA-C allotypes, known to serve as major ligands for inhibitory receptors of NK cells, can be classified into group 1 (C1) and group 2 (C2), based on their ...[more]