Diagnostic significance of urinary long non-coding PCA3 RNA in prostate cancer.
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ABSTRACT:
SUBMITTER: Wang T
PROVIDER: S-EPMC5601676 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Publications
Diagnostic significance of urinary long non-coding PCA3 RNA in prostate cancer.
Wang Tao T Qu Xiangyun X Jiang Jiajia J Gao Peng P Zhao Dingding D Lian Xueqi X Li Xiaohua X
Oncotarget 20170420 35
Prostate cancer antigen 3(PCA3) is a long non-coding RNA, which was found increased expression in CaP patients than healthy individual. In this study, the individual nucleic acid of PCA3 and PSA was recombinant expressed as a reference reagent, and a quantitative RT-PCR with TaqMan assay was developed to examine the copies of PCA3 and PSA gene in urine. The results showed that the area under the receiver operating characteristic curve (AUROC) was 0.717, 0.444 and 0.916 for the number of PCA3 cop ...[more]
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