Ontology highlight
ABSTRACT:
SUBMITTER: Xu J
PROVIDER: S-EPMC5603541 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Xu Jian J Zhang Xixi X Zhou Shuanghai S Shen Junjun J Yang Dawei D Wu Jing J Li Xiaoyang X Li Meiling M Huang Xiufen X Sealy Joshua E JE Iqbal Munir M Li Yongqing Y
Scientific reports 20170918 1
Bovine herpesvirus 1 (BoHV-1) is an important pathogen of domestic and wild cattle responsible for major economic losses in dairy and beef industries throughout the world. Inhibition of viral entry plays a crucial role in the control of BoHV-1 infection and aptamers have been reported to inhibit viral replication. In this study, nine DNA aptamers that target BoHV-1 were generated using systemic evolution of ligands by exponential enrichment. Of the nine candidates, aptamer IBRV-A4 exhibited the ...[more]