Ontology highlight
ABSTRACT:
SUBMITTER: Brent AJ
PROVIDER: S-EPMC5603584 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Brent Andrew J AJ Mugo Daisy D Musyimi Robert R Mutiso Agnes A Morpeth Susan C SC Levin Michael M Scott J Anthony G JAG
Scientific reports 20170918 1
Childhood TB diagnosis is challenging. Studies in adults suggest Microscopic Observation Drug Susceptibility (MODS) culture or the Xpert MTB/RIF assay might be used to expand bacteriological diagnosis. However data from children are more limited. We prospectively compared MODS and Xpert MTB/RIF with standard microscopy and culture using the BD MGIT 960 system among 1442 Kenyan children with suspected TB. 97 specimens from 54 children were TB culture-positive: 91 (94%) by MGIT and 74 (76%) by MOD ...[more]