Combining radiotherapy with immunotherapy: the past, the present and the future.
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ABSTRACT:
SUBMITTER: Van Limbergen EJ
PROVIDER: S-EPMC5603954 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Publications
Combining radiotherapy with immunotherapy: the past, the present and the future.
Van Limbergen Evert J EJ De Ruysscher Dirk K DK Olivo Pimentel Veronica V Marcus Damiënne D Berbee Maaike M Hoeben Ann A Rekers Nicolle N Theys Jan J Yaromina Ala A Dubois Ludwig J LJ Lambin Philippe P
The British journal of radiology 20170525 1076
The advent of immunotherapy is currently revolutionizing the field of oncology, where different drugs are used to stimulate different steps in a failing cancer immune response chain. This review gives a basic overview of the immune response against cancer, as well as the historical and current evidence on the interaction of radiotherapy with the immune system and the different forms of immunotherapy. Furthermore the review elaborates on the many open questions on how to exploit this interaction ...[more]
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