Ontology highlight
ABSTRACT:
SUBMITTER: Young E
PROVIDER: S-EPMC5605236 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Young Eleanor E Pastor Steven S Rajagopalan Ramakrishnan R McCaffrey Jennifer J Sibert Justin J Mak Angel C Y ACY Kwok Pui-Yan PY Riethman Harold H Xiao Ming M
Nucleic acids research 20170501 9
Accurate maps and DNA sequences for human subtelomere regions, along with detailed knowledge of subtelomere variation and long-range telomere-terminal haplotypes in individuals, are critical for understanding telomere function and its roles in human biology. Here, we use a highly automated whole genome mapping technology in nano-channel arrays to analyze large terminal human chromosome segments extending from chromosome-specific subtelomere sequences through subtelomeric repeat regions to termin ...[more]