Ontology highlight
ABSTRACT:
SUBMITTER: Egerton A
PROVIDER: S-EPMC5605255 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Egerton Alice A Howes Oliver D OD Houle Sylvain S McKenzie Kwame K Valmaggia Lucia R LR Bagby Michael R MR Tseng Huai-Hsuan HH Bloomfield Michael A P MA Kenk Miran M Bhattacharyya Sagnik S Suridjan Ivonne I Chaddock Chistopher A CA Winton-Brown Toby T TT Allen Paul P Rusjan Pablo P Remington Gary G Meyer-Lindenberg Andreas A McGuire Philip K PK Mizrahi Romina R
Schizophrenia bulletin 20170301 2
Migration is a major risk factor for schizophrenia but the neurochemical processes involved are unknown. One candidate mechanism is through elevations in striatal dopamine synthesis and release. The objective of this research was to determine whether striatal dopamine function is elevated in immigrants compared to nonimmigrants and the relationship with psychosis. Two complementary case-control studies of in vivo dopamine function (stress-induced dopamine release and dopamine synthesis capacity) ...[more]