Characterisation and risk assessment of venous thromboembolism in gastrointestinal cancers.

ABSTRACT:

Aim

To characterise venous thromboembolism (VTE) in gastrointestinal cancer and assess the clinical utility of risk stratification scoring.

Methods

We performed a retrospective analysis using electronic patient records of 910 gastro-oesophageal (GO) cancer and 1299 colorectal cancer (CRC) patients referred to a tertiary cancer centre to identify the incidence of VTE, its relationship to chemotherapy and impact on survival. VTE risk scores were calculated using the Khorana index. Patients were classified as low risk (0 points), intermediate risk (1 to 2 points) or high risk (3 points). Data was analysed to determine the sensitivity of the Khorana score to predict VTE.

Results

The incidence of VTE was 8.9% for CRC patients and 9.7% for GO cancer patients. Pulmonary embo

SUBMITTER: Metcalf RL 

PROVIDER: S-EPMC5605336 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature