Anatomical and functional organization of the human substantia nigra and its connections.
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ABSTRACT:
SUBMITTER: Zhang Y
PROVIDER: S-EPMC5606848 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Publications
Anatomical and functional organization of the human substantia nigra and its connections.
Zhang Yu Y Larcher Kevin Michel-Herve KM Misic Bratislav B Dagher Alain A
eLife 20170821
We investigated the anatomical and functional organization of the human substantia nigra (SN) using diffusion and functional MRI data from the Human Connectome Project. We identified a tripartite connectivity-based parcellation of SN with a limbic, cognitive, motor arrangement. The medial SN connects with limbic striatal and cortical regions and encodes value (greater response to monetary wins than losses during fMRI), while the ventral SN connects with associative regions of cortex and striatum ...[more]
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