Ontology highlight
ABSTRACT:
SUBMITTER: Hur M
PROVIDER: S-EPMC5606849 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Hur Matthew M Gistelinck Charlotte A CA Huber Philippe P Lee Jane J Thompson Marjorie H MH Monstad-Rios Adrian T AT Watson Claire J CJ McMenamin Sarah K SK Willaert Andy A Parichy David M DM Coucke Paul P Kwon Ronald Y RY
eLife 20170908
Phenomics, which ideally involves in-depth phenotyping at the whole-organism scale, may enhance our functional understanding of genetic variation. Here, we demonstrate methods to profile hundreds of phenotypic measures comprised of morphological and densitometric traits at a large number of sites within the axial skeleton of adult zebrafish. We show the potential for vertebral patterns to confer heightened sensitivity, with similar specificity, in discriminating mutant populations compared to an ...[more]