Ontology highlight
ABSTRACT:
SUBMITTER: Chiba S
PROVIDER: S-EPMC5607274 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Scientific reports 20170920 1
We propose a new iterative screening contest method to identify target protein inhibitors. After conducting a compound screening contest in 2014, we report results acquired from a contest held in 2015 in this study. Our aims were to identify target enzyme inhibitors and to benchmark a variety of computer-aided drug discovery methods under identical experimental conditions. In both contests, we employed the tyrosine-protein kinase Yes as an example target protein. Participating groups virtually s ...[more]