Structural-functional analysis of engineered protein-nanoparticle assemblies using graphene microelectrodes.
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ABSTRACT:
SUBMITTER: Ping J
PROVIDER: S-EPMC5607901 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Publications
Structural-functional analysis of engineered protein-nanoparticle assemblies using graphene microelectrodes.
Ping Jinglei J Pulsipher Katherine W KW Vishnubhotla Ramya R Villegas Jose A JA Hicks Tacey L TL Honig Stephanie S Saven Jeffery G JG Dmochowski Ivan J IJ Johnson A T Charlie ATC
Chemical science 20170613 8
The characterization of protein-nanoparticle assemblies in solution remains a challenge. We demonstrate a technique based on a graphene microelectrode for structural-functional analysis of model systems composed of nanoparticles enclosed in open-pore and closed-pore ferritin molecules. The method readily resolves the difference in accessibility of the enclosed nanoparticle for charge transfer and offers the prospect for quantitative analysis of pore-mediated transport, while shedding light on th ...[more]
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