Ontology highlight
ABSTRACT:
SUBMITTER: Guertin KA
PROVIDER: S-EPMC5608021 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Guertin Kristin A KA Li Xinmin S XS Graubard Barry I BI Albanes Demetrius D Weinstein Stephanie J SJ Goedert James J JJ Wang Zeneng Z Hazen Stanley L SL Sinha Rashmi R
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20170111 6
<b>Background:</b> Trimethylamine N-oxide (TMAO), a choline-derived metabolite produced by gut microbiota, and its biomarker precursors have not been adequately evaluated in relation to colorectal cancer risk.<b>Methods:</b> We investigated the relationship between serum concentrations of TMAO and its biomarker precursors (choline, carnitine, and betaine) and incident colorectal cancer risk in a nested case-control study of male smokers in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (A ...[more]