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ABSTRACT: Background
To clarify the role of physical activity in preventing disability in Japan, we investigated the association between amount of leisure-time physical activity and incidence of disability among the young elderly.Methods
In the New Integrated Suburban Seniority Investigation (NISSIN) project conducted from 1996 to 2013, we followed 2888 community-dwelling adults aged 64-65 years with no history of cerebrovascular disease for a median follow-up of 11.6 years. Disabilities were defined as follows based on the classifications of the Japanese long-term care insurance system: 1) support or care levels (support levels 1-2 or care levels 1-5); 2) care levels 2-5; 3) support or care levels with dementia; and 4) care levels 2-5 or death. In addition, we also assessed 5) all-cause mortality.Results
After controlling for sociodemographic, lifestyle, and medical factors, male participants reporting an activity level of 18.1 metabolic equivalent (MET)-hours/week (the median among those with activities) or more had 52% less risk of being classified as support or care levels with dementia compared with the no activity group (hazard ratio 0.48; 95% confidence interval, 0.25-0.94). No significant association was found among women between amount of leisure-time physical activity and incidence of disability.Conclusion
We identified an inverse dose-response relationship between the amount of leisure-time physical activity and the risk of disability with dementia in men. Therefore, a higher level of physical activity should be recommended to young elderly men to prevent disability with dementia.
SUBMITTER: Matsunaga T
PROVIDER: S-EPMC5608599 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Matsunaga Takashi T Naito Mariko M Wakai Kenji K Ukawa Shigekazu S Zhao Wenjing W Okabayashi Satoe S Ando Masahiko M Kawamura Takashi T Tamakoshi Akiko A
Journal of epidemiology 20170609 11
<h4>Background</h4>To clarify the role of physical activity in preventing disability in Japan, we investigated the association between amount of leisure-time physical activity and incidence of disability among the young elderly.<h4>Methods</h4>In the New Integrated Suburban Seniority Investigation (NISSIN) project conducted from 1996 to 2013, we followed 2888 community-dwelling adults aged 64-65 years with no history of cerebrovascular disease for a median follow-up of 11.6 years. Disabilities w ...[more]