Groupwise envelope models for imaging genetic analysis.
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ABSTRACT:
SUBMITTER: Park Y
PROVIDER: S-EPMC5608647 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Publications
Groupwise envelope models for imaging genetic analysis.
Park Yeonhee Y Su Zhihua Z Zhu Hongtu H
Biometrics 20170321 4
Motivated by searching for associations between genetic variants and brain imaging phenotypes, the aim of this article is to develop a groupwise envelope model for multivariate linear regression in order to establish the association between both multivariate responses and covariates. The groupwise envelope model allows for both distinct regression coefficients and distinct error structures for different groups. Statistically, the proposed envelope model can dramatically improve efficiency of tes ...[more]
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