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Identification of Plasmid-Mediated Quinolone Resistance in Salmonella Isolated from Swine Ceca and Retail Pork Chops in the United States.


ABSTRACT: Fluoroquinolones are important antimicrobial drugs used to treat human Salmonella infections, and resistance is rare in the United States for isolates from human and animal sources. Recently, a number of Salmonella isolates from swine cecal contents and retail pork products from National Antimicrobial Resistance Monitoring System (NARMS) surveillance exhibited decreased susceptibility to ciprofloxacin. We identified two qnrB19 quinolone resistance plasmids that are predominantly responsible for this phenomenon and found them distributed among several Salmonella serotypes isolated throughout the United States.

SUBMITTER: Tyson GH 

PROVIDER: S-EPMC5610501 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature

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Identification of Plasmid-Mediated Quinolone Resistance in Salmonella Isolated from Swine Ceca and Retail Pork Chops in the United States.

Tyson Gregory H GH   Tate Heather P HP   Zhao Shaohua S   Li Cong C   Dessai Uday U   Simmons Mustafa M   McDermott Patrick F PF  

Antimicrobial agents and chemotherapy 20170922 10


Fluoroquinolones are important antimicrobial drugs used to treat human <i>Salmonella</i> infections, and resistance is rare in the United States for isolates from human and animal sources. Recently, a number of <i>Salmonella</i> isolates from swine cecal contents and retail pork products from National Antimicrobial Resistance Monitoring System (NARMS) surveillance exhibited decreased susceptibility to ciprofloxacin. We identified two <i>qnrB19</i> quinolone resistance plasmids that are predomina  ...[more]

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