Ontology highlight
ABSTRACT:
SUBMITTER: Gross R
PROVIDER: S-EPMC5612381 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Gross Robert R Bellamy Scarlett L SL Ratshaa Bakgaki B Han Xiaoyan X Vujkovic Marijana M Aplenc Richard R Steenhoff Andrew P AP Mosepele Mosepele M Moorthy Ganesh G Zuppa Athena F AF Strom Brian L BL Bisson Gregory P GP
AIDS (London, England) 20170901 15
<h4>Objectives</h4>To determine the association between cytochrome p450 2B6 genotypes and efavirenz-based HIV treatment outcomes.<h4>Design</h4>Observational cohort study of HIV-infected adults initiating efavirenz-based regimens in Botswana.<h4>Methods</h4>The primary endpoint was a composite of death or loss to care or HIV RNA more than 25 copies/ml at 6 months. CYP2B6 516G>T and 983T>C genotyping was done with Taqman Open Array platform. Adverse experiences were measured by using the Subject ...[more]