Ontology highlight
ABSTRACT:
SUBMITTER: Vandemeulebroecke M
PROVIDER: S-EPMC5613212 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Vandemeulebroecke Marc M Bornkamp Björn B Krahnke Tillmann T Mielke Johanna J Monsch Andreas A Quarg Peter P
CPT: pharmacometrics & systems pharmacology 20170829 9
For drug development in neurodegenerative diseases such as Alzheimer's disease, it is important to understand which cognitive domains carry the most information on the earliest signs of cognitive decline, and which subject characteristics are associated with a faster decline. A longitudinal Item Response Theory (IRT) model was developed for the Basel Study on the Elderly, in which the Consortium to Establish a Registry for Alzheimer's Disease - Neuropsychological Assessment Battery (with additio ...[more]