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Effectiveness of Vildagliptin in Clinical Practice: Pooled Analysis of Three Korean Observational Studies (the VICTORY Study).


ABSTRACT: The present observational study aimed to evaluate the clinical effectiveness of vildagliptin with metformin in Korean patients with type 2 diabetes mellitus (T2DM). Data were pooled from the vildagliptin postmarketing survey (PMS), the vildagliptin/metformin fixed drug combination (DC) PMS, and a retrospective observational study of vildagliptin/metformin (fixed DC or free DC). The effectiveness endpoint was the proportion of patients who achieved a glycemic target (HbA1c) of ?7.0% at 24 weeks. In total, 4303 patients were included in the analysis; of these, 2087 patients were eligible. The mean patient age was 56.99?±?11.25 years. Overall, 58.94% patients achieved an HbA1c target of ?7.0% at 24 weeks. The glycemic target achievement rate was significantly greater in patients with baseline HbA1c?

SUBMITTER: Suh S 

PROVIDER: S-EPMC5613692 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature

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Effectiveness of Vildagliptin in Clinical Practice: Pooled Analysis of Three Korean Observational Studies (the VICTORY Study).

Suh Sunghwan S   Song Sun Ok SO   Kim Jae Hyeon JH   Cho Hyungjin H   Lee Woo Je WJ   Lee Byung-Wan BW  

Journal of diabetes research 20170824


The present observational study aimed to evaluate the clinical effectiveness of vildagliptin with metformin in Korean patients with type 2 diabetes mellitus (T2DM). Data were pooled from the vildagliptin postmarketing survey (PMS), the vildagliptin/metformin fixed drug combination (DC) PMS, and a retrospective observational study of vildagliptin/metformin (fixed DC or free DC). The effectiveness endpoint was the proportion of patients who achieved a glycemic target (HbA1c) of ≤7.0% at 24 weeks.  ...[more]

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