A secreted antibacterial neuropeptide shapes the microbiome of Hydra.
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ABSTRACT:
SUBMITTER: Augustin R
PROVIDER: S-EPMC5614986 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Publications
A secreted antibacterial neuropeptide shapes the microbiome of Hydra.
Augustin René R Schröder Katja K Murillo Rincón Andrea P AP Fraune Sebastian S Anton-Erxleben Friederike F Herbst Eva-Maria EM Wittlieb Jörg J Schwentner Martin M Grötzinger Joachim J Wassenaar Trudy M TM Bosch Thomas C G TCG
Nature communications 20170926 1
Colonization of body epithelial surfaces with a highly specific microbial community is a fundamental feature of all animals, yet the underlying mechanisms by which these communities are selected and maintained are not well understood. Here, we show that sensory and ganglion neurons in the ectodermal epithelium of the model organism hydra (a member of the animal phylum Cnidaria) secrete neuropeptides with antibacterial activity that may shape the microbiome on the body surface. In particular, a s ...[more]
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