Ontology highlight
ABSTRACT:
SUBMITTER: Bruekers SMC
PROVIDER: S-EPMC5615062 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Bruekers Stéphanie M C SMC Bao Min M Hendriks José M A JMA Mulder Klaas W KW Huck Wilhelm T S WTS
Scientific reports 20170926 1
Cells are complex systems in which dynamic gene expression and protein-interaction networks adapt to changes in the environment. Seeding and subsequent spreading of cells on substrates represents an example of adaptation to a major perturbation. The formation of adhesive interactions and self-organisation of the cytoskeleton during initial spreading might prime future cell behaviour. To elucidate the role of these events on later cellular behaviour, we mapped the trajectories by which cells resp ...[more]