Ontology highlight
ABSTRACT:
SUBMITTER: Docea AO
PROVIDER: S-EPMC5615117 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Toxicology reports 20170526
The association between genetic variations in the cytochrome P450 (CYP) family genes and pathological conditions related to long-term exposure to organochlorine compounds (OCs) deserves further elucidation. OCs are persistent organic pollutants with bioaccumulative and lipophilic characteristics. They can act as endocrine disruptors and perturb cellular mechanisms. Prolonged exposure to OCs has been associated with different pathological manifestations. CYP genes are responsible for transcribing ...[more]