Dataset Information

Effects of exposure to cadmium in sperm cells of zebrafish, Danio rerio.

ABSTRACT: Cadmium is a natural element found in the earth's crust; it is usually associated with other metals, but due to the impacts caused by human activity, its concentration has increased in the aquatic environment. This metal may damage aquatic animal reproduction, decreasing the rate of fertilization of organisms such as fish. Thus, this study aimed to evaluate the in vitro toxicity of different concentrations of cadmium (0 (control), 0.5, 5, and 10 ?g/L) using sperm cells of model organism zebrafish, Danio rerio. Structural parameters, including integrity and fluidity of the plasma membrane, concentration of oxygen species, mitochondrial function and DNA fragmentation were measured by flow cytometry. The following sperm movement parameters were also measured using the computer assisted sperm analysis (CASA) system: motility, time of motility, curvilinear velocity, average path velocity and straight line velocity in ?m/s. Significant effects were observed on path speed, straight speed, curvilinear velocity, motility time, progressive and total motility, and plasma and DNA integrity. The results showed that cadmium can negatively affect some reproductive parameters in D. rerio, which may reduce the fertility rate of these animals.

SUBMITTER: Acosta IB

PROVIDER: S-EPMC5616012 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature

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Effects of exposure to cadmium in sperm cells of zebrafish, <i>Danio rerio</i>.

Acosta Izani Bonel IB Junior Antonio Sergio Varela ASV E Silva Estela Fernandes EF Cardoso Tainã Figueiredo TF Caldas Jôsie Schwartz JS Jardim Rodrigo Desessards RD Corcini Carine Dahl CD

Toxicology reports 20160810

Cadmium is a natural element found in the earth's crust; it is usually associated with other metals, but due to the impacts caused by human activity, its concentration has increased in the aquatic environment. This metal may damage aquatic animal reproduction, decreasing the rate of fertilization of organisms such as fish. Thus, this study aimed to evaluate the <i>in vitro</i> toxicity of different concentrations of cadmium (0 (control), 0.5, 5, and 10 μg/L) using sperm cells of model organism z ...[more]

PMID: 28959594

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Dataset Information

Effects of exposure to cadmium in sperm cells of zebrafish, Danio rerio.

Publications

Effects of exposure to cadmium in sperm cells of zebrafish, <i>Danio rerio</i>.

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