MicroRNA-96 Regulates Apoptosis by Targeting PDCD4 in Human Glioma Cells.
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ABSTRACT:
SUBMITTER: Ma QQ
PROVIDER: S-EPMC5616120 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Publications
MicroRNA-96 Regulates Apoptosis by Targeting PDCD4 in Human Glioma Cells.
Ma Qing-Qing QQ Huang Jian-Ting JT Xiong Yun-Gang YG Yang Xiao-Yan XY Han Ran R Zhu Wang-Wen WW
Technology in cancer research & treatment 20160707 1
Glioblastoma multiforme, the most common and aggressive form of primary brain tumor, presents a dismal prognosis. MicroRNAs play a critical role in the initiation, progression, and metastasis of cancer; however, the potential biological role of miRNAs in glioblastoma multiforme remains largely unknown. In our study, we found that microRNA-96 is upregulated in glioma tissues than in normal human brains. Transfection of microRNA-96 mimics into glioma cells significantly decreases apoptosis by supp ...[more]
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