Ontology highlight
ABSTRACT:
SUBMITTER: Guo P
PROVIDER: S-EPMC5616130 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Guo Pu P Paul Ananya A Kumar Arvind A Harika Narinder K NK Wang Siming S Farahat Abdelbasset A AA Boykin David W DW Wilson W David WD
Chemical communications (Cambridge, England) 20170907 75
The design and synthesis of compounds that target mixed, AT/GC, DNA sequences is described. The design concept connects two N-methyl-benzimidazole-thiophene single GC recognition units with a flexible linker that lets the compound fit the shape and twist of the DNA minor groove while covering a full turn of the double helix. ...[more]