Ontology highlight
ABSTRACT:
SUBMITTER: Shen J
PROVIDER: S-EPMC5617295 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Shen Jia J Lai De-Hua DH Wilson R Alan RA Chen Yun-Fu YF Wang Li-Fu LF Yu Zi-Long ZL Li Mei-Yu MY He Ping P Hide Geoff G Sun Xi X Yang Ting-Bao TB Wu Zhong-Dao ZD Ayala Francisco J FJ Lun Zhao-Rong ZR
Proceedings of the National Academy of Sciences of the United States of America 20170905 38
Human schistosomiasis, caused by <i>Schistosoma</i> species, is a major public health problem affecting more than 700 million people in 78 countries, with over 40 mammalian host reservoir species complicating the transmission ecosystem. The primary cause of morbidity is considered to be granulomas induced by fertilized eggs of schistosomes in the liver and intestines. Some host species, like rats (<i>Rattus norvegicus</i>), are naturally intolerant to <i>Schistosoma japonicum</i> infection, and ...[more]