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Syntheses of three naturally occurring polybrominated 3,3'-bi-1H-indoles.

ABSTRACT: The naturally occurring polybrominated indoles 2,2',5,5'-tetrabromo-3,3'-bi-1H-indole, 2,2',6,6'-tetrabromo-3,3'-bi-1H-indole, and 2,2',5,5',6,6'-hexabromo-3,3'-bi-1H-indole were synthesized using a palladium catalyzed, carbon monoxide mediated, double reductive N-heterocyclization of 2,3-bis(2-nitro-4(or 5)-bromophenyl)-1,4-butadienes as the key step.

SUBMITTER: Ansari NH

PROVIDER: S-EPMC5617639 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature

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Syntheses of three naturally occurring polybrominated 3,3'-bi-1H-indoles.

Ansari Nurul H NH Taylor Matthew C MC Söderberg Björn C G BCG

Tetrahedron letters 20170203 11

The naturally occurring polybrominated indoles 2,2',5,5'-tetrabromo-3,3'-bi-1H-indole, 2,2',6,6'-tetrabromo-3,3'-bi-1H-indole, and 2,2',5,5',6,6'-hexabromo-3,3'-bi-1H-indole were synthesized using a palladium catalyzed, carbon monoxide mediated, double reductive N-heterocyclization of 2,3-bis(2-nitro-4(or 5)-bromophenyl)-1,4-butadienes as the key step. ...[more]

PMID: 28966402

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