Ontology highlight
ABSTRACT:
SUBMITTER: Chitnis T
PROVIDER: S-EPMC5617655 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Chitnis Tanuja T Weiner Howard L HL
The Journal of clinical investigation 20170905 10
There is an increasing recognition that inflammation plays a critical role in neurodegenerative diseases of the CNS, including Alzheimer's disease, amyotrophic lateral sclerosis, Parkinson's disease, and the prototypic neuroinflammatory disease multiple sclerosis (MS). Differential immune responses involving the adaptive versus the innate immune system are observed at various stages of neurodegenerative diseases, and may not only drive disease processes but could serve as therapeutic targets. On ...[more]