Ontology highlight
ABSTRACT:
SUBMITTER: Mathai BJ
PROVIDER: S-EPMC5617967 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Mathai Benan John BJ Meijer Annemarie H AH Simonsen Anne A
Cells 20170709 3
Autophagy is an evolutionarily conserved catabolic process which allows lysosomal degradation of complex cytoplasmic components into basic biomolecules that are recycled for further cellular use. Autophagy is critical for cellular homeostasis and for degradation of misfolded proteins and damaged organelles as well as intracellular pathogens. The role of autophagy in protection against age-related diseases and a plethora of other diseases is now coming to light; assisted by several divergent euka ...[more]