Ontology highlight
ABSTRACT:
SUBMITTER: Winograd EK
PROVIDER: S-EPMC5619015 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Winograd Evan K EK Ciesielski Michael J MJ Fenstermaker Robert A RA
Immunotherapy 20161101 11
Glioblastoma is the most common primary brain cancer. Aggressive treatment with surgery, radiation therapy and chemotherapy provides limited overall survival benefit. Glioblastomas have a formidable tumor microenvironment that is hostile to immunological effector cells and these cancers produce profound systemic immunosuppression. However, surgical resection of these tumors creates conditions that favor the use of immunotherapeutic strategies. Therefore, extensive surgical resection, when feasib ...[more]