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Identification of a Fragmented Small GTPase Capable of Conditional Effector Binding.


ABSTRACT: A fragmented small GTPase capable of conditional effector binding is described. The effector binding function of this split-GTPase can be modulated using a small molecule input, thus allowing for the potential design of cellular signaling pathways.

SUBMITTER: Zhao J 

PROVIDER: S-EPMC5619660 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature

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Identification of a Fragmented Small GTPase Capable of Conditional Effector Binding.

Zhao Jia J   Stains Cliff I CI  

RSC advances 20170222 20


A fragmented small GTPase capable of conditional effector binding is described. The effector binding function of this split-GTPase can be modulated using a small molecule input, thus allowing for the potential design of cellular signaling pathways. ...[more]

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