Ontology highlight
ABSTRACT:
SUBMITTER: Truini A
PROVIDER: S-EPMC5620283 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Truini Anna A Coco Simona S Nadal Ernest E Genova Carlo C Mora Marco M Dal Bello Maria Giovanna MG Vanni Irene I Alama Angela A Rijavec Erika E Biello Federica F Barletta Giulia G Merlo Domenico Franco DF Valentino Alessandro A Ferro Paola P Ravetti Gian Luigi GL Stigliani Sara S Vigani Antonella A Fedeli Franco F Beer David G DG Roncella Silvio S Grossi Francesco F
Oncotarget 20170802 40
Malignant pleural mesothelioma (MPM) is an aggressive tumor with a dismal overall survival (OS) and to date no molecular markers are available to guide patient management. This study aimed to identify a prognostic miRNA signature in MPM patients who did not undergo tumor resection. Whole miRNA profiling using a microarray platform was performed using biopsies on 27 unresected MPM patients with distinct clinical outcome: 15 patients had short survival (OS<12 months) and 12 patients had long survi ...[more]